| Thursday 8. September 2022 |
| |
U.S. Open Cup - Playoffs - Finals | 2022 |
Odds 1x2 |
| Orlando City | 3 - 0
| Sacramento Republic | 1.46 | 4.18 | 5.68 |
| |
| Thursday 28. July 2022 |
| |
|
U.S. Open Cup - Playoffs - 1/2 Finals | 2022 |
Odds 1x2 |
| Sacramento Republic | 1 - 0
pen
| Sporting Kansas City | 2.79 | 3.21 | 2.45 |
| Orlando City | 5 - 1
| New York Red Bulls | 2.57 | 3.19 | 2.61 |
| |
| Thursday 30. June 2022 |
| |
|
U.S. Open Cup - Playoffs - 1/4 Finals | 2022 |
Odds 1x2 |
| Orlando City | 2 - 1
pen
| Nashville SC | 2.27 | 3.17 | 3.02 |
| |
| Thursday 23. June 2022 |
| |
| New York Red Bulls | 3 - 0
| New York City FC | 2.47 | 3.34 | 2.61 |
| |
| Wednesday 22. June 2022 |
| |
| Los Angeles Galaxy | 1 - 2
| Sacramento Republic | 1.54 | 4.34 | 5.09 |
| |
| Thursday 26. May 2022 |
| |
|
U.S. Open Cup - Playoffs - 1/8 Finals | 2022 |
Odds 1x2 |
| Los Angeles Galaxy | 3 - 1
| Los Angeles FC | 2.42 | 3.52 | 2.57 |
| Sacramento Republic | 2 - 0
| San Jose Earthquakes | 3.00 | 3.36 | 2.17 |
| Sporting Kansas City | 2 - 1
| Houston Dynamo | 2.03 | 3.38 | 3.31 |
| New York Red Bulls | 3 - 1
| Charlotte FC | 1.67 | 3.73 | 4.77 |
| New York City FC | 1 - 0
AET
| New England Revolution | 1.75 | 3.69 | 3.99 |
| Louisville City | 1 - 2
| Nashville SC | 3.18 | 3.27 | 2.09 |
| Orlando City | 1 - 0
pen
| Inter Miami CF | 1.64 | 3.79 | 4.65 |
| |
| Thursday 12. May 2022 |
| |
|
U.S. Open Cup - Playoffs - 1/16 Finals | 2022 |
Odds 1x2 |
| Minnesota United FC | 2 - 1
| Colorado Rapids | 1.98 | 3.37 | 3.30 |
| Sacramento Republic | 2 - 0
| Phoenix Rising | 2.71 | 3.21 | 2.34 |
| Seattle Sounders | 2 - 3
pen
| San Jose Earthquakes | 1.83 | 3.55 | 3.69 |
| Houston Dynamo | 1 - 0
| San Antonio FC | 1.55 | 3.77 | 5.35 |
| Minnesota United FC | 1 - 1
| Colorado Rapids | 1.98 | 3.37 | 3.30 |
| Nashville SC | 3 - 2
AET
| Atlanta United | 1.97 | 3.18 | 3.78 |
| New England Revolution | 5 - 1
| FC Cincinnati | 1.58 | 3.81 | 4.80 |
| |
| Wednesday 11. May 2022 |
| |
| Richmond Kickers | 1 - 5
| Charlotte FC | | | |
| Los Angeles FC | 2 - 0
| Portland Timbers | 1.50 | 4.14 | 5.16 |
| Sporting Kansas City | 4 - 2
AET
| FC Dallas Burn | 2.24 | 3.20 | 2.92 |
| DC United | 0 - 3
| New York Red Bulls | 2.60 | 3.26 | 2.40 |
| Detroit City FC | 1 - 2
pen
| Louisville City | | | |
| Orlando City | 2 - 1
| Philadelphia Union | 2.15 | 3.26 | 2.95 |
| |
| Thursday 21. April 2022 |
| |
|
U.S. Open Cup - Playoffs | 2022 |
Odds 1x2 |
| Los Angeles FC | 5 - 1
| Orange County SC | 1.25 | 4.79 | 9.44 |
| Phoenix Rising | 2 - 1
| New Mexico United | | | |
| San Antonio FC | 2 - 1
AET
| Austin FC | 3.50 | 3.73 | 1.76 |
| Atlanta United | 6 - 0
| Chattanooga FC | 1.06 | 8.18 | 23.85 |
| Forward Madison | 0 - 2
| Minnesota United FC | 13.28 | 6.17 | 1.13 |
| Hartford Athletic | 1 - 2
| New York Red Bulls | 20.50 | 7.40 | 1.07 |
| Orlando City | 2 - 1
| Tampa Bay Rowdies | 1.56 | 4.24 | 4.80 |
| |
| Wednesday 20. April 2022 |
| |
| Los Angeles Galaxy | 1 - 0
| San Diego Loyal | 1.39 | 4.76 | 5.49 |
| FC Dallas Burn | 2 - 1
| FC Tulsa | 1.25 | 5.11 | 8.28 |
| Houston Dynamo | 2 - 1
| Rio Grande Valley | 1.35 | 4.49 | 6.29 |
| Detroit City FC | 2 - 1
| Columbus Crew | | | |
| FC Cincinnati | 2 - 0
AET
| Pittsburgh Riverhounds | 1.75 | 3.54 | 3.82 |
| Miami FC | 0 - 1
| Inter Miami CF | 3.51 | 3.42 | 1.81 |
| |
| Friday 8. April 2022 |
| |
| Sacramento Republic | 6 - 0
| Portland Timbers B | | | |
| Chattanooga FC | 3 - 1
| Memphis 901 | | | |
| |
| Thursday 7. April 2022 |
| |
| FC Tucson | 3 - 2
| Las Vegas Lights | | | |
| Miami FC | 3 - 0
| Miami United | 1.16 | 6.40 | 10.00 |
| North Carolina | 1 - 2
| Rio Grande Valley | | | |
| |
| Wednesday 6. April 2022 |
| |
| FC Tulsa | 2 - 1
| Tulsa Athletics | | | |
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